Ontology highlight
ABSTRACT:
SUBMITTER: Kuhbacher A
PROVIDER: S-EPMC6282100 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Kühbacher Andreas A Novy Karel K Quereda Juan J JJ Sachse Martin M Moya-Nilges Maryse M Wollscheid Bernd B Cossart Pascale P Pizarro-Cerdá Javier J
Pathogens and disease 20181101 8
Listeria monocytogenes is a pathogenic bacterium that invades epithelial cells by activating host signaling cascades, which promote bacterial engulfment within a phagosome. The pore-forming toxin listeriolysin O (LLO), which is required for bacteria phagosomal escape, has also been associated with the activation of several signaling pathways when secreted by extracellular bacteria, including Ca2+ influx and promotion of L. monocytogenes entry. Quantitative host surfaceome analysis revealed signi ...[more]