Inflammatory neuroprotection following traumatic brain injury.
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ABSTRACT:
SUBMITTER: Russo MV
PROVIDER: S-EPMC5260471 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Publications
Inflammatory neuroprotection following traumatic brain injury.
Russo Matthew V MV McGavern Dorian B DB
Science (New York, N.Y.) 20160801 6301
Traumatic brain injury (TBI) elicits an inflammatory response in the central nervous system (CNS) that involves both resident and peripheral immune cells. Neuroinflammation can persist for years following a single TBI and may contribute to neurodegeneration. However, administration of anti-inflammatory drugs shortly after injury was not effective in the treatment of TBI patients. Some components of the neuroinflammatory response seem to play a beneficial role in the acute phase of TBI. Indeed, f ...[more]
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