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A highly fluorescent nucleoside analog based on thieno[3,4-d]pyrimidine senses mismatched pairing.

ABSTRACT: A highly emissive nucleobase analog, based on a thieno[3,4-d]pyrimidine core, is enzymatically incorporated into RNA oilgonucleotides that function as base discriminating fluorescent probes.

SUBMITTER: Srivatsan SG

PROVIDER: S-EPMC5263222 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature

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A highly fluorescent nucleoside analog based on thieno[3,4-d]pyrimidine senses mismatched pairing.

Srivatsan Seergazhi G SG Weizman Haim H Tor Yitzhak Y

Organic & biomolecular chemistry 20080310 8

A highly emissive nucleobase analog, based on a thieno[3,4-d]pyrimidine core, is enzymatically incorporated into RNA oilgonucleotides that function as base discriminating fluorescent probes. ...[more]

PMID: 18385838

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