Ontology highlight
ABSTRACT:
SUBMITTER: Parras CM
PROVIDER: S-EPMC526464 | biostudies-literature | 2004 Nov
REPOSITORIES: biostudies-literature
Parras Carlos M CM Galli Rossella R Britz Olivier O Soares Sylvia S Galichet Christophe C Battiste James J Johnson Jane E JE Nakafuku Masato M Vescovi Angelo A Guillemot François F
The EMBO journal 20041021 22
Progenitors in the telencephalic subventricular zone (SVZ) remain mitotically active throughout life, and produce different cell types at embryonic, postnatal and adult stages. Here we show that Mash1, an important proneural gene in the embryonic telencephalon, is broadly expressed in the postnatal SVZ, in progenitors for both neuronal and oligodendrocyte lineages. Moreover, Mash1 is required at birth for the generation of a large fraction of neuronal and oligodendrocyte precursors from the olfa ...[more]