Ontology highlight
ABSTRACT:
SUBMITTER: Schrode P
PROVIDER: S-EPMC5270523 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Schrode Pius P Huter Paul P Clementi Nina N Erlacher Matthias M
RNA biology 20161114 1
Ribosomal decoding is an essential process in every living cell. During protein synthesis the 30S ribosomal subunit needs to accomplish binding and accurate decoding of mRNAs. From mutational studies and high-resolution crystal structures nucleotides G530, A1492 and A1493 of the 16S rRNA came into focus as important elements for the decoding process. Recent crystallographic data challenged the so far accepted model for the decoding mechanism. To biochemically investigate decoding in greater deta ...[more]