Ontology highlight
ABSTRACT:
SUBMITTER: Zultanski SL
PROVIDER: S-EPMC5273591 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20160516 20
A modular Cu/ABNO catalyst system has been identified that enables efficient aerobic oxidative coupling of alcohols and amines to amides. All four permutations of benzylic/aliphatic alcohols and primary/secondary amines are viable in this reaction, enabling broad access to secondary and tertiary amides. The reactions exhibit excellent functional group compatibility and are complete within 30 min-3 h at rt. All components of the catalyst system are commercially available. ...[more]