Ontology highlight
ABSTRACT:
SUBMITTER: Wu Z
PROVIDER: S-EPMC5954618 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Chemical science 20151027 2
The rhodium-catalyzed oxidative amidation of allylic alcohols and aldehydes is reported. <i>In situ</i> generated [(BINAP)Rh]BF<sub>4</sub> catalyzes the one-pot isomerization/oxidative amidation of allylic alcohols or direct amidation of aldehydes using acetone or styrene as the hydrogen acceptor. The conditions are general, affording good to excellent yields with a wide array of amine and aniline nucleophiles, and chemoselective, other alcohols do not participate in the oxidation reaction. Uti ...[more]