Ontology highlight
ABSTRACT:
SUBMITTER: Dang TT
PROVIDER: S-EPMC5279724 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Dang Tram T TT Bratlie Kaitlin M KM Bogatyrev Said R SR Chen Xiao Y XY Langer Robert R Anderson Daniel G DG
Biomaterials 20110323 19
In general, biomaterials induce a non-specific host response when implanted in the body. This reaction has the potential to interfere with the function of the implanted materials. One method for controlling the host response is through local, controlled-release of anti-inflammatory agents. Herein, we investigate the spatial and temporal effects of an anti-inflammatory drug on the cellular dynamics of the innate immune response to subcutaneously implanted poly(lactic-co-glycolic) microparticles. ...[more]