Ontology highlight
ABSTRACT:
SUBMITTER: Culurgioni S
PROVIDER: S-EPMC5287374 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Culurgioni Simone S Tang Minzhe M Walsh Martin Austin MA
Acta crystallographica. Section F, Structural biology communications 20170101 Pt 1
Streptococcus pneumoniae is an opportunistic respiratory pathogen that remains a major cause of morbidity and mortality globally, with infants and the elderly at the highest risk. S. pneumoniae relies entirely on carbohydrates as a source of carbon and dedicates a third of all uptake systems to carbohydrate import. The structure of the carbohydrate-free substrate-binding protein SP0092 at 1.61 Å resolution reveals it to belong to the newly proposed subclass G of substrate-binding proteins, with ...[more]