Ontology highlight
ABSTRACT:
SUBMITTER: Nie Y
PROVIDER: S-EPMC5288731 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Nie Yaping Y Chen Hu H Guo Cilin C Yuan Zhuning Z Zhou Xingyu X Zhang Ying Y Zhang Xumeng X Mo Delin D Chen Yaosheng Y
Scientific reports 20170202
Differentiation of myoblasts is essential in the development and regeneration of skeletal muscles to form multinucleated, contractile muscle fibers. However, the process of myoblast differentiation in mammals is complicated and requires to be further investigated. In this study, we found Palmdelphin (Palmd), a cytosolic protein, promotes myoblast differentiation. Palmd is predominantly expressed in the cytosol of myoblasts and is gradually up-regulated after differentiation. Knockdown of Palmd b ...[more]