Ontology highlight
ABSTRACT:
SUBMITTER: Na JH
PROVIDER: S-EPMC5291082 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Na Jung-Hyun JH Lee Won-Kyu WK Kim Yuyoung Y Jeong Cherlhyun C Song Seung Soo SS Cha Sun-Shin SS Han Kyou-Hoon KH Shin Yeon-Kyun YK Yu Yeon Gyu YG
Biochemical and biophysical research communications 20160611 2
Nucleolar phosphoprotein 140 (Nopp140) is a nucleolar protein, more than 80% of which is disordered. Previous studies have shown that the C-terminal region of Nopp140 (residues 568-596) interacts with protein kinase CK2α, and inhibits the catalytic activity of CK2. Although the region of Nopp140 responsible for the interaction with CK2α was identified, the structural features and the effect of this interaction on the structure of Nopp140 have not been defined due to the difficulty of structural ...[more]