Ontology highlight
ABSTRACT:
SUBMITTER: Devarie-Baez NO
PROVIDER: S-EPMC5292231 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Devarie-Baez Nelmi O NO Silva Lopez Elsa I EI Furdui Cristina M CM
Free radical research 20151111 2
Selective modification of proteins at cysteine residues by reactive oxygen, nitrogen or sulfur species formed under physiological and pathological states is emerging as a critical regulator of protein activity impacting cellular function. This review focuses primarily on protein sulfenylation (-SOH), a metastable reversible modification connecting reduced cysteine thiols to many products of cysteine oxidation. An overview is first provided on the chemistry principles underlining synthesis, stabi ...[more]