Ontology highlight
ABSTRACT:
SUBMITTER: Chen F
PROVIDER: S-EPMC5292741 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Chen Feng F Jiang Rihua R Wang Yicun Y Zhu Mingji M Zhang Xu X Dong Shuai S Shi Hongxi H Wang Li L
Scientific reports 20170206
Sporothrix globosa is a type of fungus that typically infects immunocompromised patients. Its prevention continues to pose a challenge. A 70-KDa glycoprotein (Gp70) of Sporothrix has been previously reported to protect host against infection from this fungus. Here, we displayed an epitope peptide (kpvqhalltplgldr) of Gp70 on the major coat protein (pIII), and investigated its efficiency as a vaccine for preventing S. globosa infection. The recombinant phage and the heat-killed S. globosa were us ...[more]