Ontology highlight
ABSTRACT:
SUBMITTER: Cheah SY
PROVIDER: S-EPMC5295009 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Cheah Sern-Yih SY Lawford Bruce R BR Young Ross McD RM Morris Charles P CP Voisey Joanne J
Genes 20170104 1
Serotonin receptor 2A (<i>HTR2A</i>) is an important signalling factor implicated in cognitive functions and known to be associated with schizophrenia. The biological significance of <i>HTR2A</i> in schizophrenia remains unclear as molecular analyses including genetic association, mRNA expression and methylation studies have reported inconsistent results. In this study, we examine <i>HTR2A</i> expression and methylation and the interaction with <i>HTR2A</i> polymorphisms to identify their biolog ...[more]