Association between serotonin 2A receptor (HTR2A) genetic variations and risk of hypertension in a community-based cohort study.
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ABSTRACT:
SUBMITTER: Choi JR
PROVIDER: S-EPMC6943889 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
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Association between serotonin 2A receptor (HTR2A) genetic variations and risk of hypertension in a community-based cohort study.
Choi Jung Ran JR Jeon Minhee M Koh Sang Baek SB
BMC medical genetics 20200106 1
<h4>Background</h4>Hypertension is one of the risk factors for obesity-related cardiovascular diseases. We investigated whether genetic variations in serotonin 2A receptor (HTR2A) were associated with hypertension.<h4>Methods</h4>We carried out a cross-sectional study in cohorts A (Ansan-Ansung cohort, N = 6039) and B (Wonju-Pyengchang cohort, N = 7524). Several genetic variants in HTR2A including rs7330636, rs9590999, rs2183057, and rs4942595 were selected and genotyped.<h4>Results</h4>In hyper ...[more]
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