Ontology highlight
ABSTRACT:
SUBMITTER: Awadasseid A
PROVIDER: S-EPMC5298263 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Awadasseid Annoor A Hou Jie J Gamallat Yaser Y Xueqi Shang S Eugene Kuugbee D KD Musa Hago Ahmed A Bamba Djibril D Meyiah Abdo A Gift Chiwala C Xin Yi Y
PloS one 20170208 2
Cancer is one of the most common causes of deaths worldwide. Herein, we report an efficient natural anticancer glucan (CVG) extracted from Coriolus Versicolar (CV). CVG was extracted by the hot water extraction method followed by ethanol precipitation and purified using gas exclusion chromatography. Structural analysis revealed that CVG has a linear α-glucan chain composed of only (1→ 6)-α-D-Glcp. The antitumor activity of CVG on Sarcoma-180 cells was investigated in vitro and in vivo. Mice were ...[more]