Ontology highlight
ABSTRACT:
SUBMITTER: Adachi S
PROVIDER: S-EPMC5304688 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Adachi Shinya S Kumagai Naoya N Shibasaki Masakatsu M
Chemical science 20160923 1
For decades, the planarity of the amide functional group has garnered sustained interest in organic chemistry, enticing chemists to deform its usually characteristic high-fidelity plane. As opposed to the construction of amides that are distorted by imposing rigid covalent bond assemblies, we demonstrate herein the deformation of the amide plane through increased steric bulk in the periphery of the amide moiety, which is induced by coordination to metal cations. A crystallographic analysis revea ...[more]