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Proteases of haematophagous arthropod vectors are involved in blood-feeding, yolk formation and immunity - a review.

ABSTRACT: Ticks, triatomines, mosquitoes and sand flies comprise a large number of haematophagous arthropods considered vectors of human infectious diseases. While consuming blood to obtain the nutrients necessary to carry on life functions, these insects can transmit pathogenic microorganisms to the vertebrate host. Among the molecules related to the blood-feeding habit, proteases play an essential role. In this review, we provide a panorama of proteases from arthropod vectors involved in haematophagy, in digestion, in egg development and in immunity. As these molecules act in central biological processes, proteases from haematophagous vectors of infectious diseases may influence vector competence to transmit pathogens to their prey, and thus could be valuable targets for vectorial control.

SUBMITTER: Santiago PB

PROVIDER: S-EPMC5307778 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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Proteases of haematophagous arthropod vectors are involved in blood-feeding, yolk formation and immunity - a review.

Santiago Paula Beatriz PB de Araújo Carla Nunes CN Motta Flávia Nader FN Praça Yanna Reis YR Charneau Sébastien S Bastos Izabela M Dourado IM Santana Jaime M JM

Parasites & vectors 20170213 1

Ticks, triatomines, mosquitoes and sand flies comprise a large number of haematophagous arthropods considered vectors of human infectious diseases. While consuming blood to obtain the nutrients necessary to carry on life functions, these insects can transmit pathogenic microorganisms to the vertebrate host. Among the molecules related to the blood-feeding habit, proteases play an essential role. In this review, we provide a panorama of proteases from arthropod vectors involved in haematophagy, i ...[more]

PMID: 28193252

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