Unknown

Dataset Information

0

The prognostic value of interim positron emission tomography scan in patients with classical Hodgkin lymphoma.

ABSTRACT: The prognostic value of interim positron emission tomography (PET) was evaluated after 2 cycles of doxorubicin, bleomycin, vinblastin and dacarbazine in classical Hodgkin lymphoma patients (n = 229), based on Deauville criteria. In early stage non-bulky disease, bulky stage II disease, advanced stage low International Prognostic Score (IPS ?2) and advanced stage (IPS ?3), 3-year progression-free survival rates in PET2-negative vs. PET2-positive groups were 95·9% vs. 76·9% (P < 0·0018), 83·3% vs. 20·0% (P = 0·017), 77·0% vs. 30·0% (P < 0·001) and 71·0% vs. 44·4%(P = 0·155), respectively. The outcome after positive PET2 was better than previously reported. The results from non-randomized studies of PET2-guided therapy would be valuable with careful interpretation.

SUBMITTER: Oki Y 

PROVIDER: S-EPMC5308126 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

The prognostic value of interim positron emission tomography (PET) was evaluated after 2 cycles of doxorubicin, bleomycin, vinblastin and dacarbazine in classical Hodgkin lymphoma patients (n = 229), based on Deauville criteria. In early stage non-bulky disease, bulky stage II disease, advanced stage low International Prognostic Score (IPS ≤2) and advanced stage (IPS ≥3), 3-year progression-free survival rates in PET2-negative vs. PET2-positive groups were 95·9% vs. 76·9% (P < 0·0018), 83·3% vs.  ...[more]

Similar Datasets

Unknown Pretransplantation fluorine-18-deoxyglucose--positron emission tomography scan lacks prognostic value in chemosensitive B cell non-hodgkin lymphoma patients undergoing nonmyeloablative allogeneic stem cell transplantation.
| S-EPMC5716350 | biostudies-literature
Unknown Prognostic Value of Baseline and Interim Positron Emission Tomography Markers in Diffuse Large B-cell Lymphoma Patients: A Real-world Perspective.
| S-EPMC8274798 | biostudies-literature
Unknown Prognostic impact of interim positron emission tomography in mantle cell lymphoma patients treated with frontline R-CHOP.
| S-EPMC7155042 | biostudies-literature
Unknown Relationship between semiquantitative <sup>18</sup>F-fluorodeoxyglucose positron emission tomography metrics and necrosis in classical Hodgkin lymphoma.
| S-EPMC6667466 | biostudies-literature
Unknown Quantitative evaluation of interim positron emission tomography in peripheral T-cell lymphoma.
| S-EPMC8440745 | biostudies-literature
Unknown Predictive value of interim positron emission tomography in diffuse large B-cell lymphoma: a systematic review and meta-analysis.
| S-EPMC6267696 | biostudies-literature
Transcriptomics Genomic signature of the standardized uptake value in 18F-fluorodeoxyglucose positron emission tomography in breast cancer
2020-03-18 | GSE131769 | GEO
Transcriptomics Gene expression profiles of the standardized uptake value in 18F-fluorodeoxyglucose positron emission tomography in tripple negative breast cancer
2020-03-18 | GSE135565 | GEO
Unknown The predictive role of interim positron emission tomography for Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria of the Deauville five-point scale.
| S-EPMC4040916 | biostudies-other
Unknown Consolidation radiotherapy following positron emission tomography complete response in early-stage Hodgkin lymphoma: a meta-analysis.
| S-EPMC7422924 | biostudies-literature