Role of Streptococcus pneumoniae Proteins in Evasion of Complement-Mediated Immunity.
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ABSTRACT:
SUBMITTER: Andre GO
PROVIDER: S-EPMC5316553 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Role of <i>Streptococcus pneumoniae</i> Proteins in Evasion of Complement-Mediated Immunity.
Andre Greiciely O GO Converso Thiago R TR Politano Walter R WR Ferraz Lucio F C LF Ribeiro Marcelo L ML Leite Luciana C C LC Darrieux Michelle M
Frontiers in microbiology 20170220
The complement system plays a central role in immune defense against <i>Streptococcus pneumoniae</i>. In order to evade complement attack, pneumococci have evolved a number of mechanisms that limit complement mediated opsonization and subsequent phagocytosis. This review focuses on the strategies employed by pneumococci to circumvent complement mediated immunity, both <i>in vitro</i> and <i>in vivo</i>. At last, since many of the proteins involved in interactions with complement components are v ...[more]
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