Ontology highlight
ABSTRACT:
SUBMITTER: Liu NQ
PROVIDER: S-EPMC5316867 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Nature communications 20170214
Genome-wide association studies have identified a great number of non-coding risk variants for colorectal cancer (CRC). To date, the majority of these variants have not been functionally studied. Identification of allele-specific transcription factor (TF) binding is of great importance to understand regulatory consequences of such variants. A recently developed proteome-wide analysis of disease-associated SNPs (PWAS) enables identification of TF-DNA interactions in an unbiased manner. Here we pe ...[more]