Ontology highlight
ABSTRACT:
SUBMITTER: Zhu B
PROVIDER: S-EPMC5319882 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Zhu Bo B Wei Lan L Rotile Nicholas N Day Helen H Rietz Tyson T Farrar Christian T CT Lauwers Gregory Y GY Tanabe Kenneth K KK Rosen Bruce B Fuchs Bryan C BC Caravan Peter P
Hepatology (Baltimore, Md.) 20161231 3
Hepatic fibrosis is associated with an overproduction of matrix proteins and a pathological increase of liver stiffness. Noninvasive magnetic resonance (MR) quantification of matrix can be assessed with a collagen-binding molecular MR probe and stiffness by MR elastography, complementary techniques. This study used both imaging techniques to more accurately stage hepatic fibrosis in a rat model. Thirty rats with varying levels of diethylnitrosamine-induced liver fibrosis were imaged before and 4 ...[more]