Ontology highlight
ABSTRACT:
SUBMITTER: Karvellas CJ
PROVIDER: S-EPMC5319885 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Hepatology (Baltimore, Md.) 20170119 3
Acetaminophen (APAP)-induced acute liver failure (ALF) is associated with significant mortality. Traditional prognostic scores lack sensitivity. Serum liver-type fatty acid binding protein (FABP1) early (day 1) or late (day 3-5) levels are associated with 21-day mortality in the absence of liver transplant. Serum samples from 198 APAP-ALF patients (nested case-control study with 99 survivors, 99 nonsurvivors) were analyzed by enzyme-linked immunosorbent assay with clinical data from the US Acute ...[more]