Ontology highlight
ABSTRACT:
SUBMITTER: Choi YH
PROVIDER: S-EPMC5319907 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Biometrics 20160705 1
In this article, we propose an association model to estimate the penetrance (risk) of successive cancers in the presence of competing risks. The association between the successive events is modeled via a copula and a proportional hazards model is specified for each competing event. This work is motivated by the analysis of successive cancers for people with Lynch Syndrome in the presence of competing risks. The proposed inference procedure is adapted to handle missing genetic covariates and sele ...[more]