Ontology highlight
ABSTRACT:
SUBMITTER: Gosain A
PROVIDER: S-EPMC5321668 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Pediatric surgery international 20160119 4
Hirschsprung's disease (HSCR) is a common cause of neonatal bowel obstruction and the approach to diagnosis and surgical treatment is well defined and accepted. Hirschsprung's-associated enterocolitis (HAEC) remains a frequent cause of pre-operative and post-operative morbidity and mortality, with unchanged treatment guidelines over multiple decades. Recent advances in our understanding of the genetics underlying HSCR have allowed the development of animal models, some of which recapitulate the ...[more]