Evidence for Critical Role of Lymphocyte Cytosolic Protein 1 in Oral Cancer.
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ABSTRACT:
SUBMITTER: Koide N
PROVIDER: S-EPMC5322526 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
Evidence for Critical Role of Lymphocyte Cytosolic Protein 1 in Oral Cancer.
Koide Nao N Kasamatsu Atsushi A Endo-Sakamoto Yosuke Y Ishida Sho S Shimizu Toshihiro T Kimura Yasushi Y Miyamoto Isao I Yoshimura Shusaku S Shiiba Masashi M Tanzawa Hideki H Uzawa Katsuhiro K
Scientific reports 20170223
Lymphocyte cytosolic protein 1 (LCP1), a member of actin-binding protein of the plastin family, has been identified in several malignant tumors of non-hematopoietic sites, such as the colon, prostate, and breast. However, little is known about the roles of LCP1 in oral squamous cell carcinomas (OSCCs). This present study sought to clarify the clinical relevance of LCP1 in OSCCs and investigate possible clinical applications for treating OSCCs by regulating LCP1 expression. We found up-regulation ...[more]
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