Long-term Impact of Temporal Sequence from Childhood Obesity to Hyperinsulinemia on Adult Metabolic Syndrome and Diabetes: The Bogalusa Heart Study.
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SUBMITTER: Zhang T
PROVIDER: S-EPMC5322533 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
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Long-term Impact of Temporal Sequence from Childhood Obesity to Hyperinsulinemia on Adult Metabolic Syndrome and Diabetes: The Bogalusa Heart Study.
Zhang Tao T Zhang Huijie H Li Ying Y Li Shengxu S Fernandez Camilo C Bazzano Lydia L He Jiang J Xue Fuzhong F Chen Wei W
Scientific reports 20170223
This study aims to delineate the temporal relations between body mass index (BMI) and insulin in childhood and their impact on adult metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM).The longitudinal cohort consisted of 609 whites and 339 blacks who had BMI and fasting insulin measured twice in childhood (mean age = 10.5 years at baseline and 15.9 years at follow-up). Incident MetS and T2DM were identified in adulthood (mean age = 30.5 years). Cross-lagged panel and mediation analysi ...[more]
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