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Disseminated phaeohyphomycosis in a dog.

ABSTRACT: Phaeohyphomycosis is a rare but emerging disease caused by dematiaceous fungi. Here we describe the case of an immunosuppressed dog with disseminated phaeohyphomycosis secondary to Bipolaris spicifera infection. Regionally extensive infiltration of the paw pads, skin, myocardium, liver, renal interstitium and diaphragm was identified on histopathology. Candida glabrata and Fusarium oxysporum were also cultured from multiple sites post-mortem. The dog was treated with fluconazole, itraconazole, terbinafine and liposomal amphotericin B, but was euthanized due to its poor prognosis after 12 days of therapy.

SUBMITTER: Rothenburg LS

PROVIDER: S-EPMC5328716 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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Disseminated phaeohyphomycosis in a dog.

Rothenburg Lana S LS Snider Timothy A TA Wilson Allison A Confer Anthony W AW Ramachandran Akhilesh A Mani Rinosh R Rizzi Theresa T Nafe Laura L

Medical mycology case reports 20170224

Phaeohyphomycosis is a rare but emerging disease caused by dematiaceous fungi. Here we describe the case of an immunosuppressed dog with disseminated phaeohyphomycosis secondary to Bipolaris spicifera infection. Regionally extensive infiltration of the paw pads, skin, myocardium, liver, renal interstitium and diaphragm was identified on histopathology. Candida glabrata and Fusarium oxysporum were also cultured from multiple sites post-mortem. The dog was treated with flucona ...[more]

PMID: 28275534

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