Ontology highlight
ABSTRACT:
SUBMITTER: Assar Z
PROVIDER: S-EPMC5330279 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Structure (London, England : 1993) 20160811 9
Human Cellular Retinol Binding Protein II (hCRBPII), a member of the intracellular lipid-binding protein family, is a monomeric protein responsible for the intracellular transport of retinol and retinal. Herein we report that hCRBPII forms an extensive domain-swapped dimer during bacterial expression. The domain-swapped region encompasses almost half of the protein. The dimer represents a novel structural architecture with the mouths of the two binding cavities facing each other, producing a new ...[more]