Ontology highlight
ABSTRACT:
SUBMITTER: Fuma S
PROVIDER: S-EPMC5333144 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Scientific reports 20170302
The mechanism underlying the effects of anti-vascular endothelial growth factor (VEGF) antibody in retinal vein occlusion (RVO) treatment is poorly understood, partly due to the lack of RVO animal models that mimic clinical pathology. The aims of this study were to establish a suitable RVO model, clarify the pathogenic mechanisms, and evaluate the effects of anti-VEGF antibody in the model. Mouse retinal veins were occluded by laser photocoagulation after rose bengal injection. Reduction of the ...[more]