Ontology highlight
ABSTRACT:
SUBMITTER: Ishikawa H
PROVIDER: S-EPMC5334256 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Ishikawa Hiroaki H Marshall Wallace F WF
Cold Spring Harbor perspectives in biology 20170301 3
Cilia and flagella are microtubule-based organelles whose assembly requires a motile process, known as intraflagellar transport (IFT), to bring tubulin and other components to the distal tip of the growing structure. The IFT system uses a multiprotein complex with components that appear to be specialized for the transport of different sets of cargo proteins. The mechanisms by which cargo is selected for ciliary import and transport by IFT remain an area of active research. The complex dynamics o ...[more]