Ontology highlight
ABSTRACT:
SUBMITTER: Xiao X
PROVIDER: S-EPMC5339336 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Xiao Xi X Chen Changyan C Yu Tian-Ming TM Ou Jiayao J Rui Menglong M Zhai Yuanfen Y He Yijing Y Xue Lei L Ho Margaret S MS
Frontiers in molecular neuroscience 20170307
Neuronal activity mediated by voltage-gated channels provides the basis for higher-order behavioral tasks that orchestrate life. Chaperone-mediated regulation, one of the major means to control protein quality and function, is an essential route for controlling channel activity. Here we present evidence that <i>Drosophila</i> ER chaperone Calnexin colocalizes and interacts with the α subunit of sodium channel Paralytic. Co-immunoprecipitation analysis indicates that Calnexin interacts with Paral ...[more]