Ontology highlight
ABSTRACT:
SUBMITTER: Hu J
PROVIDER: S-EPMC5342349 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Hu Jian J Chen Li L Yang Wuchen W Li Bin B Sun Heqiang H Wei Shanshan S He Yafei Y Zhao Zhuo Z Yang Shiming S Zou Quanming Q Chen Weisan W Guo Hong H Wu Chao C
Oncotarget 20160801 34
In mice, antigen-specific CD4+ T cell response is indispensible for the protective immunity against Helicobacter pylori (H. pylori). It has been demonstrated that neuraminyllactose-binding hemagglutinin (HpaA) immunization protected mice from H. pylori infection in a CD4+ T cell dependent manner. However, much remains unclear concerning the human CD4+ T cell responses to HpaA. We conducted a systematic study here to explore the immunodominant, HpaA-specific CD4+ T cell responses in H. pylori inf ...[more]