Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC5342546 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Wang Jian J Li Hai H Wang Yong Y Wang Libin L Yan Xiurui X Zhang Dong D Ma Xiaoqiang X Du Yong Y Liu Xiaoming X Yang Yinxue Y
Oncotarget 20161001 43
Colorectal cancer (CRC) is one of the most common prevalent cancer types worldwide. MicroRNAs (miRNAs or miRs) have been demonstrated to play crucial roles in the development, metastasis and drug resistance of CRC. In the present study, a strikingly elevated expression of miR-552 was determined in CRC tumor tissues and cells by a miRNA profiling analysis. Importantly, the gene of A Disintegrin And Metalloprotease (ADAM) family member 28 (ADAM28) was identified as a target of miR-552, which was f ...[more]