Ontology highlight
ABSTRACT:
SUBMITTER: Basuli F
PROVIDER: S-EPMC5344719 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Journal of labelled compounds & radiopharmaceuticals 20170201 3
Fluorine-18 labeling of biomolecules is mostly performed by an indirect labeling method using a prosthetic group. Fluorine-18 labeled 6-fluoronicotinic acid-2,3,5,6-tetrafluorophenyl ester is a useful prosthetic group to radiolabel a protein. Recently, we reported an improved preparation of this prosthetic group. To test the conjugation efficiency of the labeled ester prepared by this method, we have performed conjugation reactions with a peptide, a protein, and a small molecule. Prostate-specif ...[more]