Ontology highlight
ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC5348276 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Chen Jiayu J Calhoun Vince D VD Pearlson Godfrey D GD Perrone-Bizzozero Nora I NI Turner Jessica A JA Ehrlich Stefan S Ho Beng-Choon BC Liu Jingyu J
Schizophrenia research 20160913
Schizophrenia is a psychiatric disorder with high heritability. Recent genome-wide association studies have provided a list of risk loci reliably derived from unprecedentedly large samples. However, further delineation of the diagnosis-associated susceptibility variants is needed to better characterize the genetic architecture given the disease's complex nature. In this sense, a data-driven approach might hold promise for identifying functionally related clusters of genetic variants that might n ...[more]