Ontology highlight
ABSTRACT:
SUBMITTER: Holmes CE
PROVIDER: S-EPMC5350889 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Holmes Chris E CE Jasielec Jagoda J Levis Jamie E JE Skelly Joan J Muss Hyman B HB
Clinical and translational science 20130515 5
Aspirin has a range of antineoplastic properties linked to inhibition of cyclooxygenase enzymes in tumor cells, platelet inhibition and to inhibition of angiogenesis. We undertook a prospective study to determine the influence of a 45-day course of aspirin therapy on circulating and intraplatelet levels of selected proangiogenic (vascular endothelial growth factor [VEGF]) and antiangiogenic (thrombospondin-1 [TSP-1]) proteins, and platelet protein release in women diagnosed with breast cancer wh ...[more]