PD-L1 Expression in Lung Cancer.
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ABSTRACT:
SUBMITTER: Yu H
PROVIDER: S-EPMC5353357 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Publications
PD-L1 Expression in Lung Cancer.
Yu Hui H Boyle Theresa A TA Zhou Caicun C Rimm David L DL Hirsch Fred R FR
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20160423 7
Immunotherapies targeted against programmed death ligand 1 (PD-L1) and its receptor (PD-1) have improved survival in a subset of patients with advanced lung cancer. PD-L1 protein expression has emerged as a biomarker that predicts which patients are more likely to respond to immunotherapy. The understanding of PD-L1 as a biomarker is complicated by the history of use of different immunohistochemistry platforms with different PD-L1 antibodies, scoring systems, and positivity cut-offs for immunoth ...[more]
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