Ontology highlight
ABSTRACT:
SUBMITTER: Dela Cruz R
PROVIDER: S-EPMC5354592 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Dela Cruz Richard R Jeong Mi-Young MY Winge Dennis R DR
Microbial cell (Graz, Austria) 20160630 7
Cox23 is a known conserved assembly factor for cytochrome <i>c</i> oxidase, although its role in cytochrome <i>c</i> oxidase (CcO) biogenesis remains unresolved. To gain additional insights into its role, we isolated spontaneous suppressors of the respiratory growth defect in <i>cox23</i>∆ yeast cells. We recovered independent colonies that propagated on glycerol/lactate medium for <i>cox23</i>∆ cells at 37°C. We mapped these mutations to the mitochondrial genome and specifically to <i>COX1</i> ...[more]