Ontology highlight
ABSTRACT:
SUBMITTER: Chen CM
PROVIDER: S-EPMC5355147 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Chen Chien-Min CM Lin Chu-Liang CL Chiou Hui-Ling HL Hsieh Shu-Ching SC Lin Chia-Liang CL Cheng Chun-Wen CW Hung Chia-Hung CH Tsai Jen-Pi JP Hsieh Yi-Hsien YH
Oncotarget 20170201 8
The Endothelial cell specific molecule-1 (ESM1) protein has been involved in proliferation and metastatic progression in multiple tumors. However, there are no studies regarding the mechanism of ESM1 in prostate cancer. We found that ESM1 knockdown in prostate cancer cells resulted in increased cell proliferation and colony formation ability response evidenced by decreased expression of p21 and increased expression of cyclin D1 in prostate cancer cells. Moreover, we revealed that knockdown ESM1 ...[more]