Genomic strategies to understand causes of keratoconus.
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ABSTRACT:
SUBMITTER: Karolak JA
PROVIDER: S-EPMC5357269 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Publications
Genomic strategies to understand causes of keratoconus.
Karolak Justyna A JA Gajecka Marzena M
Molecular genetics and genomics : MGG 20161228 2
Keratoconus (KTCN) is a degenerative disorder of the eye characterized by the conical shape and thinning of the cornea. The abnormal structure of KTCN-affected cornea results in loss of visual acuity. While many studies examine how environmental factors influence disease development, finding the genetic triggers has been a major emphasis of KTCN research. This paper focuses on genomic strategies that were implemented for finding candidate genes, including linkage and association studies, and pre ...[more]
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