Dataset Information

Maternal Circadian Eating Time and Frequency Are Associated with Blood Glucose Concentrations during Pregnancy.

ABSTRACT:

Background

Synchronizing eating schedules to daily circadian rhythms may improve metabolic health, but its association with gestational glycemia is unknown.

Objective

This study examined the association of maternal night-fasting intervals and eating episodes with blood glucose concentrations during pregnancy.

Methods

This was a cross-sectional study within a prospective cohort in Singapore. Maternal 24-h dietary recalls, fasting glucose, and 2-h glucose concentrations were ascertained at 26-28 wk gestation for 1061 women (aged 30.7 ± 5.1 y). Night-fasting intervals were based on the longest fasting duration during the night (1900-0659). Eating episodes were defined as events that provided >50 kcal, with a time interval between eating episodes of ≥15 min. Multiple linear regressions with adjustment for confounders were conducted.

Results

Mean ± SD night-fasting intervals and eating episodes per day were 9.9 ± 1.6 h and 4.2 ± 1.3 times/d, respectively; fasting and 2-h glucose concentrations were 4.4 ± 0.5 and 6.6 ± 1.5 mmol/L, respectively. In adjusted models, each hourly increase in night-fasting intervals was associated with a 0.03 mmol/L decrease in fasting glucose (95% CI: -0.06, -0.01 mmol/L), whereas each additional daily eating episode was associated with a 0.15 mmol/L increase in 2-h glucose (95% CI: 0.03, 0.28 mmol/L). Conversely, night-fasting intervals and daily eating episodes were not associated with 2-h and fasting glucose, respectively.

Conclusions

Increased maternal night-fasting intervals and reduced eating episodes per day were associated with decreased fasting glucose and 2-h glucose, respectively, in the late-second trimester of pregnancy. This points to potential alternative strategies to improve glycemic control in pregnant women. This study was registered at www.clinicaltrials.gov as NCT01174875.

SUBMITTER: Loy SL

PROVIDER: S-EPMC5358748 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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Publications

Maternal Circadian Eating Time and Frequency Are Associated with Blood Glucose Concentrations during Pregnancy.

Loy See Ling SL Chan Jerry Kok Yen JK Wee Poh Hui PH Colega Marjorelee T MT Cheung Yin Bun YB Godfrey Keith M KM Kwek Kenneth K Saw Seang Mei SM Chong Yap-Seng YS Natarajan Padmapriya P Müller-Riemenschneider Falk F Lek Ngee N Chong Mary Foong-Fong MF Yap Fabian F

The Journal of nutrition 20161019 1

<h4>Background</h4>Synchronizing eating schedules to daily circadian rhythms may improve metabolic health, but its association with gestational glycemia is unknown.<h4>Objective</h4>This study examined the association of maternal night-fasting intervals and eating episodes with blood glucose concentrations during pregnancy.<h4>Methods</h4>This was a cross-sectional study within a prospective cohort in Singapore. Maternal 24-h dietary recalls, fasting glucose, and 2-h glucose concentrations were ...[more]

PMID: 27798346

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Dataset Information

Maternal Circadian Eating Time and Frequency Are Associated with Blood Glucose Concentrations during Pregnancy.

Background

Objective

Methods

Results

Conclusions

Publications

Maternal Circadian Eating Time and Frequency Are Associated with Blood Glucose Concentrations during Pregnancy.

Similar Datasets

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