Ontology highlight
ABSTRACT:
SUBMITTER: Jin T
PROVIDER: S-EPMC5363573 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Jin Tianbo T Ren Yongchao Y Zhu Xikai X Li Xun X Ouyang Yongri Y He Xue X Zhang Zhiying Z Zhang Yuan Y Kang Longli L Yuan Dongya D
Oncotarget 20161101 47
Previous studies demonstrated that Angiotensin II Receptor 1 (AGTR1) may play an important role in the development of high-altitude pulmonary edema. We envisaged a role for AGTR1 gene variants in the pathogenesis of HAPE and investigated their potential associations with HAPE in a Han Chinese population. We genotyped seven AGTR1 polymorphisms in 267 patients with diagnosed HAPE and 304 controls and evaluated their association with risk of HAPE. Statistically significant associations were found f ...[more]