Ontology highlight
ABSTRACT:
SUBMITTER: Du H
PROVIDER: S-EPMC5869773 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Du Hui H Zhao Jing J Su Zhanhai Z Liu Yongnian Y Yang Yingzhong Y
Journal of physiological anthropology 20180327 1
<h4>Background</h4>High-altitude pulmonary edema (HAPE) is a serious acute mountain sickness that mainly occurs in non-acclimatized individuals after rapid ascent to high altitude. The precise etiology of HAPE remains unclear. This study aimed to investigate whether NR3C1 gene polymorphism is associated with the susceptibility to HAPE.<h4>Methods</h4>The exons of NR3C1 gene were sequenced by a ABI 3730 DNA analyzer in 133 HAPE patients and matched 135 healthy Han Chinese controls from the Yushu ...[more]