Ontology highlight
ABSTRACT:
SUBMITTER: Li H
PROVIDER: S-EPMC5365694 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Li Haoyang H Yu Fei F Xia Shuai S Yu Yufeng Y Wang Qian Q Lv Ming M Wang Yan Y Jiang Shibo S Lu Lu L
Antimicrobial agents and chemotherapy 20170324 4
Ebola virus (EBOV), the causative pathogen of the deadly Ebola virus disease (EVD), can be transmitted via contact with EVD patients, including sexual contact with EVD survivors. At present, no licensed vaccine or therapeutic is available. In this study, we compared eight anhydride-modified proteins for their entry-inhibitory activity against the pseudovirus (PsV) carrying the envelope glycoprotein (GP) of the EBOV Zaire or Sudan species (Zaire PsV and Sudan PsV, respectively). We found that 3-h ...[more]