Ontology highlight
ABSTRACT:
SUBMITTER: Smith HJ
PROVIDER: S-EPMC5369329 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Smith Haller J HJ Straughn J Michael JM Buchsbaum Donald J DJ Arend Rebecca C RC
Gynecologic oncology reports 20170321
Despite a good initial response to chemotherapy, the majority of patients with epithelial ovarian cancer will eventually recur and die of their disease. The introduction of targeted therapies to traditional chemotherapy regimens has done little to improve overall survival in women with ovarian cancer. It has become increasingly apparent that the cancer epigenome contributes significantly to the pathogenesis of ovarian cancer and may play an important role in cell proliferation, metastasis, chemo ...[more]