Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC5370190 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Zhang Lei L Hou Yubin Y Li Zhiyuan Z Ji Xinmiao X Wang Ze Z Wang Huizhen H Tian Xiaofei X Yu Fazhi F Yang Zhenye Z Pi Li L Mitchison Timothy J TJ Lu Qingyou Q Zhang Xin X
eLife 20170228
Purified microtubules have been shown to align along the static magnetic field (SMF) in vitro because of their diamagnetic anisotropy. However, whether mitotic spindle in cells can be aligned by magnetic field has not been experimentally proved. In particular, the biological effects of SMF of above 20 T (Tesla) have never been reported. Here we found that in both CNE-2Z and RPE1 human cells spindle orients in 27 T SMF. The direction of spindle alignment depended on the extent to which chromosome ...[more]