Ontology highlight
ABSTRACT:
SUBMITTER: Nicolas S
PROVIDER: S-EPMC5371731 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Nicolas Simon S Blasco-Baque Vincent V Fournel Audren A Gilleron Jerome J Klopp Pascale P Waget Aurelie A Ceppo Franck F Marlin Alysson A Padmanabhan Roshan R Iacovoni Jason S JS Tercé François F Cani Patrice D PD Tanti Jean-François JF Burcelin Remy R Knauf Claude C Cormont Mireille M Serino Matteo M
Molecular systems biology 20170316 3
Gut microbiota dysbiosis has been implicated in a variety of systemic disorders, notably metabolic diseases including obesity and impaired liver function, but the underlying mechanisms are uncertain. To investigate this question, we transferred caecal microbiota from either obese or lean mice to antibiotic-free, conventional wild-type mice. We found that transferring obese-mouse gut microbiota to mice on normal chow (NC) acutely reduces markers of hepatic gluconeogenesis with decreased hepatic P ...[more]