Ontology highlight
ABSTRACT:
SUBMITTER: Lim DW
PROVIDER: S-EPMC5371820 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Lim Dong-Woo DW Bose Shambhunath S Wang Jing-Hua JH Choi Han Seok HS Kim Young-Mi YM Chin Young-Won YW Jeon Song-Hee SH Kim Jai-Eun JE Kim Hojun H
Scientific reports 20170330
Samjunghwan (SJH) is an herbal formula used in traditional Korean medicine. This prescription has long been used in treatment of aging and lifestyle diseases. The current study showed the effect and mechanisms of anti-hepatic steatosis action of modified SJH (mSJH) in vitro and in vivo. Treatment with mSJH resulted in significantly decreased intracellular lipid accumulation in steatosis-induced cells. Furthermore, mSJH triggered the phosphorylation of AMP-activated protein kinase and acetyl-CoA ...[more]