Fused-Ring Oxazolopyrrolopyridopyrimidine Systems with Gram-Negative Activity.
Ontology highlight
ABSTRACT: Fused polyheterocyclic derivatives are available by annulation of a tetramate scaffold, and been shown to have antibacterial activity against a Gram-negative, but not a Gram-positive, bacterial strain. While the activity is not potent, these systems are structurally novel showing, in particular, a high level of polarity, and offer potential for the optimization of antibacterial activity.
SUBMITTER: Chen Y
PROVIDER: S-EPMC5372982 | biostudies-literature |
REPOSITORIES: biostudies-literature
ACCESS DATA
